Indapamide
Filed under: Diuretics
Displayed: indapamide Natrilix 1.5mg
Indapamide is used to treat high blood pressure (hypertention) it prevents the hormone noradrenaline (norepinephrine) from constricting blood vessels, this in turn allows them to dilate. Indapamide is sometimes combined with other anti-hypertensives but is not used with other diuretics. When given in low doses the drugs effects are slight. However, having said that individuals who are susceptible need to have their blood levels of potassium and uric acid monitored. Individuals who are at risk include the elderly, those taking digitalis drugs or those with gout, or over-production of the hormone aldosterone (hyperaldosterone). Unlike other thiazides, those individuals who suffer from diabetes need not fear indapamide as the tablet does not affect control of diabetes.
The US trade name for indapamide is Lozol.
Detailed Information
your own monitor settings
Quick Guide
- Diuretic with danger of overdose – LOW
- Dependency is said to be – LOW
- Prescription only drug – YES
- Available as generic – YES
- Alcohol Avoidance – NO
- There would be no alcohol problems
Side Effects
You may if on this medication suffer one or more of these side effects, in the initial stages. However, you may find you do not suffer any at all, as it does not follow that being on this medication will cause unwanted adverse effects.
Common: Dizziness, Fatique, Headaches, Muscle Cramp
Rare: Constipation, Diarrhoea, Fainting, Impotence, Jaundice, Palpitations, Rash, Pins and Needles
Prolonged Use
Blood potassium and uric acid levels may be monitored periodically. Long term use of indapamide may lead to a drop in potassium levels in the elderly.
Driving, Hazardous Work & Alcohol
There are no special problems in these areas. This would also apply to alcohol.
Pregnancy and Breast-Feeding
Safety in pregnancy has not been established. safety has not been established in breast feeding either.
Tell Your Doctor
You should tell your doctor if you have a current health problem. For example: heart disease, kidney problems, if you are pregnant or you intend to become pregnant, or if you think you may be at risk from drug treatment for any other reason. Some types of medication can cause serious adverse effects when taken side by side so it is important to tell your doctor of any other medication you are already taking. This should also include any over-the-counter medication. For example: Painkillers, cold remedies, herbal and complimentary / alternative medication.
See full list of things you should tell your doctor about.»Over 60’s & Children
There would be no special problems for the over sixties either. This drug would not be prescribed for infants or children.
Overdose
An unintentional extra dose is unlikely to cause problems. If a large overdose has been taken or you notice unusual symptoms notify your doctor.
Other Medication Reactions
If you are considering stopping this medication you should consult your doctor first. Stopping could lead to a return of the high blood pressure. Blood levels of lithium are increased when it is taken with indapamige. If indapamide is taken along-side diuretics there is a risk of salts imbalance in the blood. A loss of potassium may lead to toxicity if digitalis medication is taken with indapamide.
Missed A Dose
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose to make up for a missed one.
Reducing or Stopping Medication
If you are considering stopping this medication you should consult your doctor first. Stopping could lead to a return of the high blood pressure.
Effect Of Medication
Effects could be felt within 1 – 2 hours however full effects may not be felt for several months. Lasting effects are between 12 – 24 hours.
Storage and Safety
Keep medicine in its original container, in a cool dry place, away from the reach of children. Never take medication that has past the expiry date shown on the box or container. Return all un-used or old medicines to your pharmacist. Do not discard old or unwanted medication into your trash, sink or toilet.
Do not leave your doctors surgery until you have a clear understanding of what the drug your doctor has prescribed for you does, and why you have been prescribed it. It is common for people who do not understand the reason behind there treatment to take their medication correctly.
- If you have/had gout
- If you have had a stroke
- If you are allergic to sulphonamides
- If you have hyperaldosteronism
- If you have hyperthyroidism
- If you are taking digitalis drugs
- You have long-term kidney or liver problems
- If you are or intend to become pregnant or you are or intend to breast feed
- If you are taking any other medication (including herbal/alternative/complementary medicine)


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