The most important group of drugs that could either precipitate diabetes as a side effect or make existing diabetes worse are such medication known as hormones. Hormones are produced by special glands in the body, insulin (Glucagon) its-self is a hormone, produced by the pancreas released automatically to reduce sugar levels in the blood, unless you suffer from either form of diabetes. (IDD) insulin dependant diabetes or (NIDD) non insulin dependant diabetes. Some hormones have what is called an anti-insulin effect.
Steroids are sometimes used in the treatment of asthma or rheumatoid arthritis. The most commonly used steroid hormone is the tablet known as prednisolone which opposes insulin causing the glucose in the blood to rise. Steroids in large doses will often precipiate diabetes however, this usually gets better when the steroids are stopped.
The contraceptive pill is another type of hormone and has a very mild anti-insulin effect. It is not unheard of people on the pill given themselves more insulin to compensate.
Conditions such as Coronary Thrombosis or severe injuries from a traffic accident may lead to diabetes. This is mainly due to the fact that most of the hormones produced in response to stress tend to have the opposite effect to insulin and cause the blood glucose levels to rise. In most people more insulin would be produced to counteract the rise in blood glucose. In some cases if reserves are low they become inadequate and would result in temporary diabetes, returning to normal once the stress was over. However there would be an increased risk of developing permanent diabetes at a later date in the future
Pancreatitis is inflamation of this gland it can very often be very painful and unpleasant. The pancreas amongst other things produces insulin and if this gland becomes scarred it may no longer be capable of producing enough of this hormone. Sometimes diabetes can develop during or after an attack of this illness. There are other diseases of the pancreas such as cancer of the pancreas and cystic fibrosis and surgical removal of the pancreas for either cancer or pancreatitis also causes diabetes. # It is possible to produce excessive amounts of steroid hormones (Cushing’s disease or Cushing’s syndrome) and this can lead to diabetes. Plus producing excessive amounts of growth hormone may also lead to diabetes