Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs and is used to treat type 2 diabetes known as non-insulin dependant diabetes mellitus. It can be used alone or combined with metformin or with a sulphonylurea or with both. It’s function is to reduce insulin resistance in fatty tissue, the skeletal muscles and in the liver. The knock on effect is the reduction of blood glucose levels. The drug does not act instantly [...]

Chlorpropamide is a sulphonylurea drug and is an oral antidiabetics. Chlorpropamide is used to treat Type 2 (non-insulin dependent) diabetes mellitus and is used in conjunction with a diet and an exercise program. Sulphonylureas are considered for patients who are not overweight, or in whom metformin is contra-indicated (inadvisable or undesirable) or not tolerated. Insulin is made naturally in the pancreas. It regulates the level of sugar in the blood. If the body does not [...]

Glibenclamide belongs to a class of drug known as sulphonylurea and is an oral antidiabetic drug. The drug is used to treat maturity onset diabetes mellitus found in adults and would be used in conjunction with a diabetic diet low in carbohydrates and fats. Glibenclamide stimulates the secretion of insulin in the pancreas, this allows the uptake of sugar into body cells, which in turn lowers the level of sugar in the blood. However, in [...]

Bromocriptine an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors and Parkinson’s disease and conditions associated with excessive prolactin production from the pituitary gland. conditions include some types of female infertility and occasionally male infertility and impotence. It is also effective in treating some benign breast conditions and other symptoms of menstrual disorders. It can also be used to suppress lactation in women who do not wish to [...]

Norethisterone is a progestogen and can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with oestrogen), or to postpone a period. Norethisterone a synthetic hormone similar to the natural female sex hormone, progestogen. It is used in a wide range of menstrual disorders. One of its uses is to the postponement of menstruation, as well as treatment for menstrual disorders.( It would be taken on certain [...]

Carbamazepine is an anticonvulsant and mood stabilizing drug used primarily in the treatment of some forms of epilepsy and prophylaxis (medical or public health measures taken in order to prevent disease or health) of bipolar disorder (manic-depressive disorder) in patients unresponsive to lithium. can also be taken as a pain killer to relieve the intermittent severe pain caused by damage to the cranial nerves (trigeminal neuralgia) and the less commonly known glossopharyngeal neuralgia it will [...]

Desmopressin is a synthetic replacement for vasopressin, the hormone that reduces urine production during sleep. It may be taken nasally, intravenously, or as a pill. Doctors prescribe desmopressin most frequently for treatment of diabetes insipidus or bed-wetting. It is the levels of vasopressin in the body which can lead to diabetes insipidus, which is the cause of continual thirst and frequent urination. Desmopressin works by limiting the amount of water that is eliminated in the [...]

Tolbutamide is a first generation potassium channel blocker, sulphonylurea oral hypoglycemic drug. An antidiabetic agent that lowers blood sugar by stimulating insulin secretion from the pancreas. It is used to treat adult diabetes (type 2 diabetes mellitus) in which there is still active secretion cells from the pancreas, it is not effective in the management of type 1 (insulin dependent) diabetes. This drug is given along side a special diet that limits carbohydrates intake. Sulphonylureas [...]

Metformin is used to treat adult diabetes (type 2) this is where the body still supplies a little insulin but not enough to sustain correct body levels. It is the first-line drug of choice for the treatment of type 2 diabetes, particularly in overweight and obese individuals in whom strict dieting has failed to control diabetes, if appropriate it may also be considered as an option in patients who are not overweight. Metformin lowers blood [...]

When diabetes cannot be controlled by exercise and diet alone then Repaglinide would be given to treat the problem as it is a drug that is used to treat non insulin dependant diabetes. Repaglinide works by stimulating the release of insulin from the pancreas. However, there needs to be some cells that still work in the pancreas for Repaglinide to work. Repaglinide may be given as mono-therapy for patients who are not overweight or for [...]

Insulin is a hormone that the body manufacters in the pancreas. and is absolutely necessary to the body’s ability to burn sugar. Insulin causes cells in the liver, muscle, and fat tissue to take up glucose from the blood, storing it as glycogen in the liver and muscle. It is given by injection to supplement or replace natural insulin in the treatment of some forms of diabetes mellitus. Indivuduals with Type 1 diabetes mellitus depend [...]

Gliclazide is an oral antidiabetic drug it belongs to a family of drugs known as sulphonylurea. Its function is to stimulate production and the secretion of insulin in the pancreas. This helps with the sugar being absorbed by the body thereby lowering the level of sugar in the blood. Insulin is made by special cells in the pancreas known as beta cells. In type 2 diabetes (non-insulin dependent diabetes) you either do not make enough [...]