Indapamide

indapamide

Indapamide is used to treat high blood pressure (hypertention) it prevents the hormone noradrenaline (norepinephrine) from constricting blood vessels, this in turn allows them to dilate. Indapamide is sometimes combined with other anti-hypertensives but is not used with other diuretics. When given in low doses the drugs effects are slight. However, having said that individuals who are susceptible need to have their blood levels of potassium and uric acid monitored. Individuals who are at risk include the elderly, those taking digitalis drugs or those with gout, or over-production of the hormone aldosterone (hyperaldosterone). Unlike other thiazides, those individuals who suffer from diabetes need not fear indapamide as the tablet does not affect control of diabetes.

The US trade name for indapamide is Lozol.


Detailed Information

Brand Name: Natrilix, Natrilix SR, Nindaxa
Supplied in: Tablets, SR-Tablets
Family Group: Thiazides diuretic
Note: Colour of medication may vary depending on manufacturer, strength, and your own monitor settings

Quick Guide

  • Diuretic with danger of overdose – LOW.
  • Dependency is said to be – LOW.
  • Prescription only drug – YES.
  • Available as generic – YES (generic drugs, short: generics) is a drug which is produced and distributed without patent protection.
  • Alcohol Avoidance – NO.
  • There would be no alcohol problems.

Side Effects

You may if on this medication suffer one or more of these side effects, in the initial stages. However, you may find you do not suffer any at all, as it does not follow that being on this medication will cause unwanted adverse effects.

Common: Dizziness, Fatique, Headaches, Muscle Cramp
Rare: Constipation, Diarrhoea, Fainting, Impotence, Jaundice, Palpitations, Rash, Pins and Needles

The side effects listed here are the most common and rare problems reported by patients using this medication It does not include all of the side effects reported by the drug’s manufacturer. If common side effects persist you need to inform your doctor. Notify your doctor if you suffer any of the rare or some other side effects not listed here. For total peace of mind, seek information from your doctor or chemist.

Prolonged Use

Blood potassium and uric acid levels may be monitored periodically. Long term use of indapamide may lead to a drop in potassium levels in the elderly.

Driving, Hazardous Work & Alcohol

There are no special problems in these areas. This would also apply to alcohol.

Pregnancy and Breast-Feeding

Safety in pregnancy has not been established. safety has not been established in breast feeding either.

Tell Your Doctor Or Pharmacist

You should tell your doctor if you have a current health problem. For example: heart disease, kidney problems, if you are pregnant or you intend to become pregnant, or if you think you may be at risk from drug treatment for any other reason. Some types of medication can cause serious adverse effects when taken side by side so it is important to tell your doctor of any other medication you are already taking. This should also include any over-the-counter medication. For example: Painkillers, cold remedies, herbal and complimentary / alternative medication.

See full list of things you should tell your doctor about.»

Over 60′s & Children

There would be no special problems for the over sixties either. This drug would not be prescribed for infants or children.

Overdose

An unintentional extra dose is unlikely to cause problems. If a large overdose has been taken or you notice unusual symptoms notify your doctor immediately.

Failing this go to your nearest accident and emergency department of your local hospital. Take the container with you. This will help the hospital staff identify what has been taken and work towards given the right kind of help without delay.

Other Medication Reactions

If you are considering stopping this medication you should consult your doctor first. Stopping could lead to a return of the high blood pressure. Blood levels of lithium are increased when it is taken with indapamige. If indapamide is taken along-side diuretics there is a risk of salts imbalance in the blood. A loss of potassium may lead to toxicity if digitalis medication is taken with indapamide.

Missed A Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose to make up for a missed one.

Reducing or Stopping Medication

If you are considering stopping this medication you should consult your doctor first. Stopping could lead to a return of the high blood pressure.

Effect Of Medication

Effects could be felt within 1 – 2 hours however full effects may not be felt for several months. Lasting effects are between 12 – 24 hours.

Storage and Safety

Keep medicine in its original container, in a cool dry place, away from the reach of children. Never take medication that has past the expiry date shown on the box or container. Return all un-used or old medicines to your pharmacist. Do not discard old or unwanted medication into your trash, sink or toilet.

If this medication has been prescribed for you never allow anyone else to use it, even if you know or others feel their symptom are similar to your own.

Do not leave your doctors surgery until you have a clear understanding of what the drug your doctor has prescribed for you does, and why you have been prescribed it. It is common for people who do not understand the reason behind there treatment to take their medication correctly.

  • If you have/had gout
  • If you have had a stroke
  • If you are allergic to sulphonamides
  • If you have hyperaldosteronism
  • If you have hyperthyroidism
  • If you are taking digitalis drugs
  • You have long-term kidney or liver problems
  • If you are or intend to become pregnant or you are or intend to breast feed
  • If you are taking any other medication (including herbal/alternative/complementary medicine)

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About the Author: The Medibolism Team

It must be stressed that we are not doctors. We only have an interest in the medication, healthy living, etc. The information on this site has been derived from personal experiences, medical leaflets, books, doctor advice, and other professional means. The medicine database is referenced to British National Formulary - 61st Edition (March 2011).

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