Norethisterone

norethisterone

Norethisterone is a progestogen and can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with oestrogen), or to postpone a period. Norethisterone a synthetic hormone similar to the natural female sex hormone, progestogen. It is used in a wide range of menstrual disorders. One of its uses is to the postponement of menstruation, as well as treatment for menstrual disorders.( It would be taken on certain days of the menstrual cycle.) It can also be used as an oral contraceptive, it is also prescribed as a hormone replacement therapy (HRT) and is also of use as a treatment for certain breast cancers. In special circumstances It can be given as an injectable contraceptive, but only under special circumstances.


Detailed Information

Brand Name: Micronor, Noriday, Noristerat, Primolut N, Utovlan
Supplied in: Injection, Tablets, Skin Patches
Family Group: Female Hormone Medication
Note: Colour of medication may vary depending on manufacturer, strength, and your own monitor settings

Quick Guide

  • Female sex hormone with danger of overdose – LOW.
  • Dependency is said to be – LOW.
  • Prescription only drug – YES.
  • Available as generic – YES. (generic drugs, short: generics) is a drug which is produced and distributed without patent protection.
  • Alcohol Avoidance – NO.

Side Effects

You may if on this medication suffer one or more of these side effects, in the initial stages. However, you may find you do not suffer any at all, as it does not follow that being on this medication will cause unwanted adverse effects.

Common: Breakthrough Bleeding
Rare: Depression, Headaches, Jaundice, Weight Gain, Swollen Feet and Ankles

The side effects listed here are the most common and rare problems reported by patients using this medication It does not include all of the side effects reported by the drug’s manufacturer. If common side effects persist you need to inform your doctor. Notify your doctor if you suffer any of the rare or some other side effects not listed here. For total peace of mind, seek information from your doctor or chemist.

Prolonged Use

It can in rare cases cause liver damage. It may be that blood test are taken to keep a safe watch on the liver.

Driving, Hazardous Work & Alcohol

There would be no special problems for this category.

Pregnancy and Breast-Feeding

Norethisterone would not usually be prescribed in pregnancy as it may cause problems for the unborn. The drug passes into the milk However, at normal doses it would be unlikely to cause a problem, if you breast feed. Discuss both these issues with your doctor.

Norethisterone is classified as a pregnancy Category X medicine by the U.S. Contraindicated in Pregnancy- Studies in animals or humans, or investigational or post-marketing reports, have demonstrated positive evidence of fetal abnormalities or risk which clearly outweighs any possible benefit to the patient.

Tell Your Doctor Or Pharmacist

You should tell your doctor if you have a current health problem. For example: heart disease, kidney problems, if you are pregnant or you intend to become pregnant, or if you think you may be at risk from drug treatment for any other reason. Some types of medication can cause serious adverse effects when taken side by side so it is important to tell your doctor of any other medication you are already taking. This should also include any over-the-counter medication. For example: Painkillers, cold remedies, herbal and complimentary / alternative medication.

See full list of things you should tell your doctor about.»

Over 60′s & Children

This drug would not normally be prescribed for the over sixties. Norethisterone would not be prescribed for infants or children.

Overdose

Although an unintentional extra dose would not give reason for concern, if you notice any unusual symptoms or a large overdose has been taken you should notify your doctor immediately.

Failing this go to your nearest accident and emergency department of your local hospital. Take the container with you. This will help the hospital staff identify what has been taken and work towards given the right kind of help without delay.

Other Medication Reactions

Ciclosporin levels may be increased by the use of norethisterone. Norethisterone may interfere with the good effects from many other drugs. These would include anticonvulsants, oral anticoagulants, antihypertensives and antidiabetic drugs. There are other drugs that may reduce the contraceptive effect of norethisterone containing-pills. Including anticonvulsants, antituberculous drugs and antibiotics. You should make your doctor aware if you are taking norethisterone before you take any more prescribed additional medication.

Missed A Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose to make up for a missed one.

Reducing or Stopping Medication

This drug can be stopped as soon as you no-longer need its contraceptive protection. However if you take the drug for an underlying disorder do not stop taking the drug without discussing it with your doctor first.

Effect Of Medication

Norethisterone begins to work within a few hours. It has lasting effects of 24 hours.

Storage and Safety

Keep medicine in its original container, in a cool dry place, away from the reach of children. Never take medication that has past the expiry date shown on the box or container. Return all un-used or old medicines to your pharmacist. Do not discard old or unwanted medication into your trash, sink or toilet.

If this medication has been prescribed for you never allow anyone else to use it, even if you know or others feel their symptom are similar to your own.

Do not leave your doctors surgery until you have a clear understanding of what the drug your doctor has prescribed for you does, and why you have been prescribed it. It is common for people who do not understand the reason behind there treatment to take their medication correctly.

  • If you have had epileptic fits or asthma.
  • If you have kidney or liver problems
  • If you are pregnant, trying for a baby or breast-feeding
  • If you have suffered from a skin condition called pemphigoid gestationis (herpes) during a previous pregnancy
  • If you have suffered from abnormal vaginal bleeding of unknown cause.
  • If you suffer from porphyria (genetic blood disorders)
  • If you have ever had an allergic reaction to this or any other medicine
  • If you suffer from poor circulation
  • If you have recently suffered chest pain or a heart attack
  • If you suffer from migraine
  • If you suffer from diabetes mellitus
  • If you are taking any other medication (including herbal/alternative/complementary medicine)

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About the Author: The Medibolism Team

It must be stressed that we are not doctors. We only have an interest in the medication, healthy living, etc. The information on this site has been derived from personal experiences, medical leaflets, books, doctor advice, and other professional means. The medicine database is referenced to British National Formulary - 61st Edition (March 2011).

4 Comments + Add Comment

  • Is 5mg of norethisterone taken at the same time daily a contraceptive? I have been given these as the mini pill but on the patient information sheet it only says they are used for heavy periods and are not a contraceptive.

    • Hi, Karen

      The mini pill contains progestogen only. The active ingredient is norethisterone a synthetic hormone similar to the natural female sex hormone and is usually taken by women who for what ever reason are unable to take the combined oral contraceptive which contains oestrogen and progestogen.

      The Mini pill prevents mucus changes around the time of ovulation so that sperm cannot get through to the egg thus preventing fertilisation. The lining of the womb (endometrium) is affected so that, even if an egg is fertilised, it is unlikely to be able to implant and develop.

      The progesterone only pill may cause menstrual irregularities, such as irregular bleeding or missed periods. These can be annoying, but tend to settle down after a while. If you have continued problems with irregular bleeding you should talk to your doctor.

      Be aware some medicines taken a long-side the mini pill on a regular basis might affect the POP (progestogen only pill). During these times additional contraception, such as condoms should be considered.

      The answer to your query is yes norethisterone is the active ingredient in the mini pill.

      Many Thanks for using our website. Its a bit late to wish you a Happy Christmas.
      But I do wish your every success and continued good health in the coming year.

      You have been given this information in response to a question left on our website. It should not be taken as a diagnosis. If you are in any doubt check it out with your doctor or pharmacist.

      medibolism team.

      NB. If pregnancy does occur, there is a greater risk of it occurring outside the womb (ectopic pregnancy) in progesterone-only pill users than in other women. For this reason, any abnormal abdominal pain occurring with an irregular menstrual cycle should be reported to your doctor.

  • my daughter has been given this drug to stop her having a period on holiday. she has just started her period early! Can she start taking this drug now so that the period is quicker or will it stop it all together or is it too late. her period normally lasts 7 days which will ruin the first 3 days of holiday!

    • Hi,

      Norethisterone is a very effective way of delaying a period when it would be inconvenient, and this is especially true at holiday times.

      If you are not taking the combined oral contraceptive pill and wish to delay a period then a hormone tablet called norethisterone can be prescribed. Normally the dose is 5 mg three times a day and must start 3-4 days before a period is due.

      It can be continued for up to two weeks or so until you want to have a period. The period will then normally begin 2-3 days after stopping norethisterone. Norethisterone is normally safe to take. It is possible that some women may suffer side effects such as bloating, stomach upset, breast discomfort and reduced libido (sex drive).

      The drug works by delaying a fall in the level of progestogen hormone in the body. When the hormone falls below a certain level, the lining of the uterus is shed as menstrual period. By taking norethisterone tablets (progestogen) the lining of the uterus is sustained until the tablet is stopped.

      Please note: Norethisterone taken in this way is not a contraceptive.

      You have been given this information in response to a question left on our website. It should not be taken as a diagnosis and has been given for information purposes only.
      If you are in any doubt check it out with your doctor or pharmacist.

      Many thanks for your visit.

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