Tibolone

Tibolone

Tibolone is a synthetic steroid that has progestogenic and some androgenic properties as well as oestrogenic effects. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women, such as sweating,depressed mood, and decreased sex drive. It is also useful to control hot flushes. Tibolone is taken continuously and, unlike most of the other hormone replacement therapies, the treatment does not require a cyclical course of proestogen to be taken as well. This is because the drug its self has both oestrogenic and progestogenic activity. Tibolone as a low incidence of side effects and does not cause withdrawal bleeding in post-menopausal women. This drug is also used to prevent osteoporois after the menopause.

Tobacco smoking increases the risk of getting a blood clot or having a stroke while you are taking tibolone, especially if you are more than 35 years old. You are strongly advised not to smoke.


Detailed Information

Brand Name: Livial
Supplied in: Tablets
Family Group: Hormone Replacement Therapy
Note: Colour of medication may vary depending on manufacturer, strength, and your own monitor settings

Quick Guide

  • Horme replacement therapy with danger of overdose – LOW
  • Dependancy is is – LOW
  • Prescription only Drug – YES
  • Available as generic – NO (generic drugs, short: generics) is a drug which is produced and distributed without patent protection.
  • Alcohol Avoidance – NO

Side Effects

You may if on this medication suffer one or more of these side effects, in the initial stages. However, you may find you do not suffer any at all, as it does not follow that being on this medication will cause unwanted adverse effects.

Common: Rash, itching, Nausea
Rare: Weight lose, Ankle SwellingHeadsche, Visual Disterbances, Dizziness, Stomach Upset, Acne, Facial Hair Growth, Vaginal Bleeding, Joint or Muscle pains, Jaundice

The side effects listed here are the most common and rare problems reported by patients using this medication It does not include all of the side effects reported by the drug’s manufacturer. If common side effects persist you need to inform your doctor. Notify your doctor if you suffer any of the rare or some other side effects not listed here. For total peace of mind, seek information from your doctor or chemist.

Prolonged Use

Periodic examination by your doctor would be advised.

Driving, Hazardous Work & Alcohol

No known problems would be expected.

Pregnancy and Breast-Feeding

Tibolone would not be prescribed

Amitriptyline is classified as a pregnancy Category C medicine by the U.S. Food and Drug Administration (FDA). Category C… Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Tell Your Doctor Or Pharmacist

You should tell your doctor if you have a current health problem. For example: heart disease, kidney problems, if you are pregnant or you intend to become pregnant, or if you think you may be at risk from drug treatment for any other reason. Some types of medication can cause serious adverse effects when taken side by side so it is important to tell your doctor of any other medication you are already taking. This should also include any over-the-counter medication. For example: Painkillers, cold remedies, herbal and complimentary / alternative medication.

See full list of things you should tell your doctor about.»

Over 60′s & Children

There would be no special problems expected.

Overdose

An unintentional extra dose would not give rise for concern. However, if a number of tablets have been taken together, they may cause a stomach upset. You should inform your doctor.

Other Medication Reactions

Some anticonvulsants such as phenytoin, phenobarbital, primodone, and carbamazepine can accelerate the metabolism of timolone and this will decrease blood levels of the drug and its effectiveness. This would also apply to Ritampicin.

Missed A Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take a double dose to make up for a missed one.

Reducing or Stopping Medication

It is possible for symptoms to recur if you stop taking this medication . You should consult with your doctor or healthcare professional at all times.

Effect Of Medication

This medication should be taken as prescribed which is usually everyday at the same time. Take the tablets whole do not chew them. For best results this medication should be taken for at least 3 months. However, you will notice an improvement after the first few weeks.

Storage and Safety

Keep medicine in its original container, in a cool dry place, away from the reach of children. Never take medication that has past the expiry date shown on the box or container. Return all un-used or old medicines to your pharmacist. Do not discard old or unwanted medication into your trash, sink or toilet.

If this medication has been prescribed for you never allow anyone else to use it, even if you know or others feel their symptom are similar to your own.

Do not leave your doctors surgery until you have a clear understanding of what the drug your doctor has prescribed for you does, and why you have been prescribed it. It is common for people who do not understand the reason behind there treatment to take their medication correctly.

  • If you suffer from migraine or epilepsy
  • If you have long term liver problems
  • If you have long term kidney problems
  • If you or any one in your family have suffered from breast cancer
  • If you have a tumour
  • If you suffer from diabetes mellitus (high blood sugar) or high blood pressure
  • If you think you may be pregnant or are thinking of becoming pregnant
  • If you have suffered from vaginal bleeding, fibroids or suffer from endometriosis
  • If you have had a period in the last 12 months
  • If you have cardiiovascular or cerebrovascular disease
  • If you have high cholesterol levels
  • If any one in your family has a history of angina, myocardial infarction, stroke or mini-stroke
  • If you suffer from endometrial hyperplasia. (increase in the number of cells in the lining of the uterus)
  • If you are taking any other medication (including herbal/alternative/complementary medicine)

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About the Author: The Medibolism Team

It must be stressed that we are not doctors. We only have an interest in the medication, healthy living, etc. The information on this site has been derived from personal experiences, medical leaflets, books, doctor advice, and other professional means. The medicine database is referenced to British National Formulary - 61st Edition (March 2011).

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