Accelerated Ageing.

Structure of the LMNA protein
Structure of the LMNA protein

Although human trials will be needed to develop the drug further it would appear that Researchers at Durham University doing research into Inherited Degenerative disorders caused by mutations in LMNA (common name Lamin A/C) gene have discovered a drug that will help DNA damaged by time repair its-self.

“This is an important step to helping children and older people live less debilitating lives,”

said their chief researcher, Professor Chris Hutchinson.

They now hope it can be used to treat conditions such as Dementia, Osteoarthritis, arthritis, cancer, and heart disease. There is also excitement the drug named N-acetyl cysteine will also stop wasting disease and premature aging in children.

Mutations in the LMNA gene are associated with several diseases, including Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb-girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, Hutchinson-Gilford progeria syndrome.

Hutchinson-Gilford’s progeroid syndrome, caused by a mutation in LMNA, is characterized by features resembling accelerated aging. This particular wasting disease causes children to age eight times faster than normal, this results in the child’s death around their 13th birthday. The head researcher Professor Chris Hutchinson said” Mutations in the LMNA cause more diseases such as muscular dystrophy than any other” If you have an interest, read the full story.